When Setting up a Windows Computer

This is current for me (a friend bought a new computer and I'll go help him set it up) . . . when you buy a new Windows system, what do you install right off the bat?

I can think of

• Firefox (and extensions--I'll list those below)
• Adobe Acrobat Reader
• iTunes
• CoolTimer
• MW Snap (screencapture)
  
• Antivirus (what kind?)
• Java/Flash/Shockwave
• Jing
• GomPlayer
• MagicDisk (if you have kids' software that is CD-dependent)
• Picasa
• Zoomit
• Skype
• Photostory
• Handbrake (ripping DVDs to MP4)
  
• PDF995 (to make pdfs or docs into jpgs for printing at Costco)
  

Firefox Extensions

• DownloadHelper
• Scrapbook
• Bookmark Current Tab Set
• Google Gears

What default settings should be changed on Windows 7?